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• Watson replaces Ollie Hassell-Collins on the left wing after the London Irish rookie sustained a knee injury in training after the round two victory over Italy
  
  The cap centurions are replaced by Ospreys’ Owen Williams and uncapped 20-year-old Cardiff centre Mason Grady, respectively
  
  Williams makes a first start in the Wales number 10 shirt after previous appearances at centre, with Grady partnered in midfield by Joe Hawkins
  
  The 28-year-old recovered from a serious knee injury to launch his Leicester career in October but has been limited to 11 outings for his new club because of other niggles
  
  Anthony Watson will make his first England start in almost two years after being recalled for Saturday’s Guinness Six Nations clash with Wales
  
  F ly-half Dan Biggar and centre George North have been left out of the Wales team
  
  
  
  An impressive replacement appearance against Scotland at the start of the Championship was Watson’s maiden red rose outing since starting against Ireland in March 2021, although he played two Tests for the Lions that same year
  
  
  
  
  
  F ly-half Dan Biggar and centre George North have been left out of the Wales team
  
  An impressive replacement appearance against Scotland at the start of the Championship was Watson’s maiden red rose outing since starting against Ireland in March 2021, although he played two Tests for the Lions that same year
  
  Anthony Watson will make his first England start in almost two years after being recalled for Saturday’s Guinness Six Nations clash with Wales
  
  Williams makes a first start in the Wales number 10 shirt after previous appearances at centre, with Grady partnered in midfield by Joe Hawkins
  
  The cap centurions are replaced by Ospreys’ Owen Williams and uncapped 20-year-old Cardiff centre Mason Grady, respectively
  
  The 28-year-old recovered from a serious knee injury to launch his Leicester career in October but has been limited to 11 outings for his new club because of other niggles
  
  Watson replaces Ollie Hassell-Collins on the left wing after the London Irish rookie sustained a knee injury in training after the round two victory over Italy